= Ornithine decarboxylase
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<Ornithine decarboxylase> converts ornithine to putrescine with release of <carbon> dioxide, beginning a major route of polyamine <biosynthesis>. Its regulation includes binding to <antizyme>, which can inhibit activity and promote <protein degradation>. This gives a compact example of controlling a metabolic pathway by changing both catalytic availability and <enzyme> lifetime. <Enzyme Nomenclature by the IUBMB>[EC 4.1.1.17, accepted name, reaction and comments]{ref}
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