= P. Palese
{c}
<P. Palese> investigated the genetic evolution of <Influenza A virus>. A 1979 study with <J. F. Young> compared <RNA> fingerprints and <peptide mapping> to infer the origins of different parts of a viral <genome>.<Evolution of human influenza A viruses in nature: recombination contributes to genetic variation of H1N1 strains by J. F. Young and P. Palese>[PNAS76, pp.6547–6551; Abstract and primary byline]{ref}
The strain A/Cal/10/78 retained the H1N1 designation, yet the analysis suggested that some internal genetic segments came from an H3N2 parent. The result supported <reassortment>: a surface subtype need not describe the ancestry of every segment in a <segmented genome>. This distinction lets a scientist ask two different questions about the same <virus>: what surface antigens it carries, and where its complete genetic material came from.<Evolution of human influenza A viruses in nature: recombination contributes to genetic variation of H1N1 strains by J. F. Young and P. Palese>[Abstract; segment-origin inference]{ref}
\Image[https://scholars.mssm.edu/files-asset/14300900/ca352a71-70b5-4434-ae7d-38a7a034cba0.jpg?f=jpg&w=160]
{title=P. Palese}
{description=Portrait identified by the https://scholars.mssm.edu/en/persons/peter-palese/[Icahn School of Medicine at Mount Sinai profile].}
Back to article page
