= Solution
The fragment might sequester another factor required for <vesicle trafficking> or <actin> organization, rather than acting through <Munc18>. For example, binding a different SNARE-associated <protein> could lower the <concentration> available for productive endogenous complexes. This is a possible <dominant-negative effect>, not evidence that the isolated N terminus contains the entire <SNARE> interaction surface.
A less specific alternative is cellular stress or reduced viability. Those effects could suppress both invadopodium formation and matrix degradation without selectively inhibiting the proposed trafficking pathway.
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