= Solution
First, <electroweak gauge invariance> places left-handed quarks in $SU(2)_L$ doublets, pairing one charge-$2/3$ flavor with one charge-$-1/3$ flavor in every generation. Second, cancellation of Standard Model <gauge anomalies> ties each colored quark doublet and its singlets to a lepton doublet and its singlet; removing either member destroys the hypercharge-anomaly cancellations. Equivalently, the weak charged current and anomaly-free chiral spectrum organize quarks into complete up-down generations, so the number of quark flavors is even.
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