Solution (source code)

= Solution

In <water>, the strongly <poor solvent> favours a compact <polymer globule>. A site-volume estimate gives
$$
\boxed{R\sim0.67\,\mathrm{nm}\times1000^{1/3}\simeq6.7\,\mathrm{nm}.}
$$
The exact numerical conversion between globule radius and rms end-to-end distance depends on its density and shape; this calculation supplies the characteristic size scale.