= Perforated patch recording
<Perforated patch recording> obtains intracellular electrical access through pores in the patch under the <patch pipette>, with less open exchange of large cytoplasmic components than conventional <whole-cell recording>. Pore <selectivity> matters: retaining some components does not guarantee unchanged <ion> <concentrations>. Monitor <patch-clamp series resistance> as access develops and distinguish a perforated patch from accidental full rupture.
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