= Platelet-derived growth factor
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= PDGF
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<PDGF> means platelet-derived growth factor, a family of signaling <protein> <ligands> for <PDGFR>. Members form <protein dimers>, including the classical AA, AB and BB combinations.<Classification of Growth Factors and Their Receptors by Anna Bafico and Stuart A. Aaronson>[Platelet-Derived Growth Factor Family: A and B chains and the three classical dimer combinations]{ref} Ligand binding can bring two <receptors> together and activate their <receptor tyrosine kinase> activity.<Platelet-derived growth factor receptor in MeSH>[Descriptor D017479: alpha and beta receptor types and ligand-induced receptor dimerization]{ref}
Release from <platelets> links PDGF to local tissue responses after injury. Nearby connective-tissue <cells> can respond by entering <cell proliferation>.<Platelet-derived growth factor in MeSH>[Descriptor D010982: platelet release and initiation of connective-tissue-cell replication]{ref}
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