= Polycomb repressive complex 2
{c}
= PRC2
{c}
{synonym}
A <chromatin> complex that catalyses H3K27 methylation, with locus-specific recruitment and developmental functions.
Its catalytic activity deposits <H3K27 methylation>, including the trimethylated state associated with many repressed developmental <genes>. Recruitment and recognition of modified <chromatin> can stabilize a regulatory state while retaining the possibility of later reversal. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 7, Chromatin Structure and Gene Regulation]{ref}
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