= Polyproline
<Polyproline> is a chain or sequence region enriched in repeated proline residues. Proline constrains backbone geometry, and some proline-rich regions adopt an extended polyproline-II <conformation>. Such regions can serve as recognition elements for interaction domains in signalling <proteins>. Sequence enrichment, <conformation> and binding function should be distinguished: a proline-rich segment does not automatically establish one fixed structure or partner. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 3, Protein Structure: backbone conformation and protein-interaction domains]{ref}
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