PRG-1 (source code)

= PRG-1
{c}

The <Caenorhabditis elegans> Piwi-family <protein> associated with 21U <piRNAs> and <germline> surveillance of <RNA> expression.

Recognition by its associated small <RNAs> helps distinguish transcripts for <germline> surveillance. Establishing a persistent silenced state additionally involves downstream pathways, so initial recognition and long-term maintenance are different stages. <piRNAs Can Trigger a Multigenerational Epigenetic Memory in the Germline of C. elegans by Alyson Ashe and others>[2012, recognition and inherited silencing]{ref}