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Measure the cluster's baryonic mass, dominated by its intracluster medium with a smaller stellar contribution, and divide it by an independently inferred total mass. If this cluster baryon fraction $f_b$ is representative of the cosmic baryon fraction, then $f_b={\Omega }_b/{\Omega }_m$. Thus the cluster baryon-fraction estimate of matter density isBig Bang nucleosynthesis constrains the baryon-to-photon ratio and hence ${\Omega }_b{h}^2$ through primordial light-element abundances. A specified $h$ converts this to ${\Omega }_b$; the cluster mass and gas-mass estimates also have distance-dependent $h$ factors, which must be used consistently. This method estimates the total nonrelativistic matter density, including baryonic and dark matter. It does not add radiation or vacuum energy to that inferred ${\Omega }_m$; in a matter-dominated interpretation the question's $\Omega$ is this matter parameter.

Primordial deuterium as a baryon-density indicator works because increasing baryon density makes the destruction of deuterium into heavier nuclei more efficient during Big Bang nucleosynthesis. Smaller inferred primordial D/H therefore implies larger ${\Omega }_b$, with the other nucleosynthesis assumptions fixed. For a fixed measured cluster baryon fraction, a smaller primordial deuterium abundance raises the inferred matter density. A low abundance caused instead by stellar processing is not a lower primordial abundance; depletion, gas ejection and the representativeness of clusters must also be assessed before identifying the cluster fraction with the cosmic one.