Rac1 (source code)

= Rac1
{c}

A <small GTPase> participating in protrusion and polarity in migrating <cells>.

<Nucleotide> exchange changes recruitment of effectors that regulate the <actin> <cytoskeleton>. Spatially restricted activity can help select a protrusive region, connecting a biochemical switch to directional <cell> movement. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 16, Regulation of the Actin Cytoskeleton]{ref}