Replication protein A (source code)

= Replication protein A

A <eukaryotic> single-stranded DNA-binding complex participating in replication, repair and signalling responses.

Binding protects exposed single-stranded <DNA> and helps recruit other factors. Its presence can reflect normal replication or a response to damaged or stalled <DNA> structures, so it is not a unique marker of one pathway. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 3, 6 and 15, protein function, translation and cell signalling]{ref}