= Richard Rodewald
{c}
<Richard Rodewald> investigated selective transport of maternal <antibodies> across the newborn rat intestine. His 1973 study followed ferritin-linked immunoglobulins and antiperoxidase antibodies through intestinal epithelial <cells>, using tracer localization to distinguish selective uptake from nonspecific entry.<Intestinal transport of antibodies in the newborn rat by Richard Rodewald>[Abstract and Discussion, pp. 202–205: immunoglobulin tracers and transport controls]{ref}
In proximal intestinal cells, suitable <antibodies> bound at the apical surface and entered transport vesicles. Contrasting tracers and intestinal regions helped show that a molecule entering a cell is not necessarily carried into the circulation. The experiment made the route and selectivity of <transcytosis> visible, rather than relying only on a final blood concentration.
Back to article page