ROS1 (source code)

= ROS1
{c}

A <plant> <DNA> glycosylase/lyase involved in active <DNA demethylation> through a repair-associated pathway.

Active replacement can counterbalance methylation-dependent silencing at selected loci. This differs from passive dilution of a mark during replication, because the modified base is enzymatically removed through a repair-linked pathway. <ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase lyase by Zhizhong Gong and others>[2002, glycosylase/lyase activity and silencing phenotype]{ref}