Securin (source code)
= Securin
An inhibitory regulator of <separase>. Its regulated destruction helps permit sister-chromatid separation.
Destruction is controlled by the <anaphase-promoting complex>, linking the cell-cycle decision to activation of the <protease> that removes a cohesion barrier. This makes <protein> turnover part of a switch that permits physical <chromosome> separation. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 3, 6 and 15, protein function, translation and cell signalling]{ref}
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