Spätzle (source code)

= Spätzle
{c}

A <ligand> whose proteolytically activated form stimulates the <Toll receptor> in <Drosophila melanogaster>.

Proteolytic processing makes the receptor-active <ligand> available at the appropriate place and time. This separates production of a precursor from creation of an active extracellular signal, allowing localization of a developmental response. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapter 21, Early Animal Development: dorsal-ventral patterning]{ref}