Subgroup analysis in meta-analysis
= Subgroup analysis in meta-analysis
Divide studies by a specified characteristic and estimate an effect in each subgroup, then test the difference using an <independent subgroup contrast in meta-analysis> or an appropriate interaction model. The test of a between-group difference is distinct from separate tests against no effect within each group. Exploratory splits can be affected by <multiple testing> and by <confounding> between study characteristics.