Tandem duplication (source code)

= Tandem duplication

A <tandem duplication> creates an additional copy of a genomic segment adjacent to the original. A duplicated <gene> can initially increase dosage, after which the copies can diverge or one can lose function. Adjacency distinguishes tandem copies from duplicates moved to distant positions. Repeated near-identical copies can also complicate <genome assembly> because short <sequencing reads> may not identify which copy they came from. <Talking Glossary of Genomic and Genetic Terms by NHGRI>[Duplication entry]{ref}