TBX3 (source code)

= TBX3
{c}

<TBX3> is a T-box <transcription factor> with developmental roles including limb, gland and cardiac patterning. It can repress or activate <gene> programmes depending on its molecular partners and regulatory context. Its developmental importance illustrates how one DNA-binding regulator can act in several organs at different times. A <phenotype> following altered expression therefore needs a specified <tissue> and stage before it can be assigned to one direct target. <NCBI Gene by the National Library of Medicine>[Homo sapiens, TBX3 record, Summary and linked functional evidence]{ref}