= Transmembrane protein
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A <transmembrane protein> has at least one <polypeptide chain> crossing the complete <lipid bilayer>. One crossing is single-pass; several crossings in one chain are multipass. <Hydrophobic> regions face the membrane interior, while <hydrophilic> regions can face <water>.<The Cell: A Molecular Approach, 2nd edition by Geoffrey M. Cooper/Cell Membranes>[The Cell: A Molecular Approach, 2nd edition by Geoffrey M. Cooper; Cell Membranes, Membrane Proteins: spanning regions, single and multiple crossings]{ref}
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