= Vacuolar proton ATPase
An ATP-driven <proton> pump that acidifies many eukaryotic endomembrane compartments.
<Hydrolysis> of <ATP> drives <proton> movement and helps establish an acidic compartment. The resulting <electrochemical gradient> supports cargo processing and coupled transport; a low luminal <pH> is actively maintained rather than an intrinsic property of all membrane <vesicles>. <Molecular Biology of the Cell, 4th edition by Bruce Alberts and others>[Chapters 3, 6 and 15, protein function, translation and cell signalling]{ref}
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