= Yasuko Murakami
{c}
<Yasuko Murakami> coauthored research on <ornithine decarboxylase>.<Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination by Yasuko Murakami and others>[publication title and author list]{ref}
<Ornithine decarboxylase> converts ornithine to putrescine with release of <carbon> dioxide, beginning a major route of polyamine <biosynthesis>. Its regulation includes binding to <antizyme>, which can inhibit activity and promote <protein degradation>. This gives a compact example of controlling a metabolic pathway by changing both catalytic availability and <enzyme> lifetime.
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