= E. Coli K-12 MG1655 gene thrL
{title2=190-255}
{title2=thr operon leader peptide}
<UniProt> entry: https://www.uniprot.org/uniprot/P0AD86[].
<NCBI> gene entry: https://www.ncbi.nlm.nih.gov/gene/944742[].
The first <gene> in the <E. Coli K-12 MG1655> genome. Remember however that <bacterial chromosome is circular>, so being the first doesn't mean much, how the choice was made: <E. Coli genome starting point>{full}.
Part of <E. Coli K-12 MG1655 operon thrLABC>.
At only 65 bp, this gene is quite small and boring. For a more interesting gene, have a look at the next gene, <e. Coli K-12 MG1655 gene thrA>.
Does something to do with <threonine>.
This is the first in the sequence thrL, thrA, thrB, thrC. This type of naming convention is quite common on related adjacent proteins, all of which must be getting <transcribed (biology)> into a single <RNA> by the same <promoter (genetics)>. As mentioned in the analysis of the <KEGG> entry for <e. Coli K-12 MG1655 gene thrA>, those A, B and C are actually directly functionally linked in a direct <metabolic pathway>.
We can see that thrL, A, B, and C are in the same <transcription unit> by browsing the list of <promoter (genetics)> at: https://biocyc.org/group?id=:ALL-PROMOTERS&orgid=ECOLI[]. By finding the first one by position we reach; https://biocyc.org/ECOLI/NEW-IMAGE?object=TU0-42486[].
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