= Ancestral sequence reconstruction
{wiki=Ancestral_sequence_reconstruction}
Ancestral sequence reconstruction (ASR) is a computational technique used in evolutionary biology to infer the genetic sequences (DNA, RNA, or protein sequences) of ancestral organisms based on the sequences of their descendant species. Researchers use ASR to hypothesize the sequences that might have existed in common ancestors, thereby providing insights into evolutionary processes, functional characteristics of ancient proteins, and the history of genetic changes over time.
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