Source: wikibot/coil-globule-transition
= Coil–globule transition
{wiki=Coil–globule_transition}
The coil–globule transition is a phenomenon observed in polymer science, particularly in the behavior of macromolecules such as proteins and synthetic polymers in solution. This transition refers to the change in the conformation of a polymer chain from a random coil (expanded, flexible form) to a globule (compact, more ordered form) in response to certain environmental conditions.