Source: wikibot/depolarization-induced-suppression-of-inhibition
= Depolarization-induced suppression of inhibition
{wiki=Depolarization-induced_suppression_of_inhibition}
Depolarization-induced suppression of inhibition (DSI) is a neurophysiological phenomenon that occurs in certain types of neurons, particularly in the central nervous system, where an increase in membrane potential (depolarization) leads to a temporary decrease in the effectiveness of inhibitory synaptic transmission.