Perturb-seq
= Perturb-seq
{wiki=Perturb-seq}
Perturb-seq is a high-throughput technique that combines genetic perturbations (such as CRISPR-based gene editing) with single-cell RNA sequencing to study gene function and cellular responses at a single-cell level. This method allows researchers to systematically investigate how perturbations in specific genes or regulatory elements affect gene expression, cellular behavior, and phenotypic traits.