= Point accepted mutation
{wiki=Point_accepted_mutation}
Point accepted mutation (PAM) is a concept primarily used in the field of molecular biology and bioinformatics, particularly in the context of protein sequence alignment and evolutionary biology. PAM matrices are used for scoring the similarity between amino acid sequences, which helps in understanding protein evolution. The term "PAM" specifically refers to "Point Accepted Mutation" matrices that were developed by Richard Durbin and his colleagues.
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