= Single-strand conformation polymorphism
{wiki=Single-strand_conformation_polymorphism}
Single-strand conformation polymorphism (SSCP) is a molecular biology technique used to detect genetic variation among single-stranded DNA (ssDNA) fragments. The fundamental principle behind SSCP is that different sequences of DNA can adopt distinct three-dimensional conformations when they are in a single-stranded state. These conformational differences can be caused by variations such as point mutations, insertions, or deletions.
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