= Temperature-sensitive mutant
{wiki=Temperature-sensitive_mutant}
A temperature-sensitive (ts) mutant is a type of mutant organism, typically a bacterium, yeast, or animal cell, that exhibits a normal phenotype at a permissive temperature but displays a different phenotype, often a phenotype related to loss of function, at a non-permissive temperature. This change in phenotype is usually due to alterations in protein structure or function caused by mutations in the genes coding for those proteins. Temperature-sensitive mutants are particularly useful in genetic research and developmental biology.
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