Source: wikibot/upstream-open-reading-frame
= Upstream open reading frame
{wiki=Upstream_open_reading_frame}
An upstream open reading frame (uORF) is a non-canonical feature found in the messenger RNA (mRNA) of eukaryotic genes that can regulate gene expression. It is called "upstream" because it is located upstream (5' region) of the main coding sequence of a gene that encodes the primary protein product.