A Cross-linked Enzyme Aggregate (CLEA) is a type of biocatalyst that involves the aggregation of enzymes and their subsequent cross-linking to enhance stability and activity in various applications. This process generally involves the following steps: 1. **Aggregation**: Enzymes are aggregated through methods such as adding salts, changes in pH, or heating. This aggregation can promote interactions between enzyme molecules that stabilize them when they are later cross-linked.

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