CS-BLAST (Consensus Sequence-based BLAST) is an algorithm that improves upon the traditional BLAST (Basic Local Alignment Search Tool) by using a consensus sequence approach to enhance the sensitivity and speed of sequence searching in large databases. It is particularly designed for comparing protein sequences and identifying homologous sequences more effectively. CS-BLAST works by constructing a consensus sequence from a set of related sequences and employing this consensus to guide the search for similar sequences in a database.

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