Southern and Eastern Serbia, a region in the country of Serbia, is divided into several administrative districts. Each district encompasses multiple municipalities and towns. Here are the key districts in Southern and Eastern Serbia: 1. **Nišava District**: This district includes the city of Niš, which is one of the largest cities in Serbia and an important cultural and economic center. 2. **Toplica District**: Known for its natural beauty, this district includes the town of Prokuplje.

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