Scanning electron cryomicroscopy

Scanning electron cryomicroscopy (cryo-SEM) is a powerful imaging technique that combines the principles of scanning electron microscopy (SEM) with cryogenic (low-temperature) preservation methods to analyze biological samples at extremely high resolutions. This method allows researchers to visualize the ultrastructure of samples while maintaining their native state, which is particularly important for biological specimens that can be sensitive to environmental conditions.