Steric effects

Steric effects refer to the influence of the spatial arrangement of atoms in a molecule on its chemical behavior and reactivity. These effects arise from the physical size and shape of molecules, particularly the presence of bulky groups that can hinder or facilitate interactions between atoms and molecules. Key points about steric effects include: 1. **Steric Hindrance**: This occurs when large groups attached to a molecule block or hinder the approach of other reactants or the alignment necessary for chemical reactions to occur.