HH-suite is a software tool designed for sensitive sequence searching and protein homology detection. It is particularly focused on finding homologous sequences in large databases using HMM-HMM (Hidden Markov Model - Hidden Markov Model) comparisons. HH-suite builds on the principles of HMMER and allows for the comparison of sequences to HMMs derived from multiple sequence alignments, enabling the identification of distant homologs that might not be detected by traditional sequence alignment methods.
Guided analytics refers to a data analytics approach that provides users with structured paths or workflows to explore and analyze data. This method often incorporates various visual aids, recommendations, and step-by-step navigation that help users, particularly those with less technical expertise, to derive insights from data effectively. Guided analytics aims to make the data analysis process more intuitive and accessible.
Genomatix is a bioinformatics company that specializes in providing software solutions and services for the analysis of genomic data. Founded in the late 1990s, Genomatix focuses on interpreting complex biological data, particularly in the fields of genomics, transcriptomics, and epigenomics. Their tools are designed to assist researchers in understanding gene regulation, discovering biomarkers, and analyzing high-throughput sequencing data.
A General Circulation Model (GCM) is a complex mathematical model used to simulate and understand the Earth's climate system, including atmospheric and oceanic processes. GCMs are fundamental tools in climate science, enabling researchers to study weather patterns, climate change, and the interaction of various components of the Earth's system.
The Future Orientation Index (FOI) is a concept often used in social sciences, particularly psychology and developmental studies, to assess how individuals or groups perceive and plan for the future. It reflects the extent to which people are oriented towards long-term goals and the degree to which they consider future consequences of their actions. Key components of the Future Orientation Index may include: 1. **Goal Setting**: The ability to establish and pursue long-term objectives.
The Finite-Difference Time-Domain (FDTD) method is a computational algorithm used to solve differential equations that describe how electromagnetic waves propagate through a medium. This technique is particularly effective for simulating wave phenomena in complex geometries and material structures. ### Key Features of FDTD: 1. **Time Domain Approach**: FDTD is a time-domain approach, meaning it computes the electromagnetic fields (electric and magnetic) as functions of both time and space.
Enthought is a software company known for its focus on scientific computing, data analysis, and visualization. Founded in 2001, Enthought provides tools, libraries, and services primarily aimed at researchers, scientists, and engineers. One of its most notable offerings is the Enthought Python Distribution (EPD), which includes a comprehensive collection of Python libraries for scientific computing and data analysis, such as NumPy, SciPy, and Matplotlib.
The Edinburgh Parallel Computing Centre (EPCC) is a leading research center located at the University of Edinburgh in Scotland. Established in 1998, EPCC specializes in high-performance computing (HPC), parallel computing, and data-intensive research. It serves as a hub for collaboration between academic researchers and industry partners, promoting the advancement of computational techniques and technologies.
The Discrete Dipole Approximation (DDA) is a numerical method used to model the scattering and absorption of electromagnetic waves by objects that are comparable in size to the wavelength of the radiation. This technique is particularly useful in studying the optical properties of particles like aerosols, biological cells, and nanostructures. In DDA, the object of interest is represented as an array of N point dipoles (or polarizable points).
DNADynamo is a software application designed for the analysis and simulation of DNA sequences. It is particularly popular in the field of molecular biology and bioinformatics. The software provides tools for various tasks such as DNA sequence assembly, alignment, and visualization. It typically allows researchers to manipulate and analyze nucleotide sequences, model genetic constructs, and generate simulations for molecular interactions and behaviors. DNADynamo may also feature functionalities for gene design, cloning simulations, and other tasks pertinent to genetic engineering and synthetic biology.
Continuous simulation refers to a modeling approach used in various fields, such as engineering, finance, operations research, and environmental science, where systems change continuously over time. Unlike discrete simulation, which models systems where changes occur at distinct intervals or steps, continuous simulation represents changes that occur in a smooth, dynamic fashion. ### Key Characteristics of Continuous Simulation: 1. **Continuous Time**: In continuous simulation, time is treated as a continuous variable.
Computer simulation is a technique used to model the behavior of real-world systems or processes through the creation of a computerized representation. This involves using algorithms and mathematical models to simulate the interactions and dynamics of various components within a system. Key aspects of computer simulation include: 1. **Modeling**: A model is created to represent the system being studied. This can involve mathematical equations, logical frameworks, or graphical representations of the system's components and their relationships.
Computational Visualistics is an interdisciplinary field that combines aspects of computer science, visual arts, and information visualization. It focuses on the development and application of computational methods to create, analyze, and interpret visual information. The aim is to better understand data through visual representation and to enhance communication and comprehension of complex concepts and datasets. Key areas within Computational Visualistics may include: 1. **Data Visualization**: Techniques and tools for representing data visually to make it easier to understand patterns, trends, and insights.
Computational transportation science is an interdisciplinary field that leverages computational methods, data analysis, and modeling techniques to study and improve transportation systems. It combines elements from transportation engineering, computer science, operations research, and applied mathematics to address various challenges in transportation, such as traffic congestion, network optimization, transportation planning, and logistics.
Computational thinking is a problem-solving process that involves a set of skills and concepts fundamental to computer science but applicable across various disciplines. It encompasses a way of thinking that enables individuals to tackle complex problems by breaking them down into manageable parts, applying systematic reasoning, and developing solutions that can be implemented algorithmically. Key components of computational thinking include: 1. **Decomposition**: Breaking down a problem into smaller, more manageable components or steps. This makes it easier to understand and solve complex issues.
Computational sustainability is an interdisciplinary field that combines concepts and techniques from computer science, mathematics, and the natural and social sciences to address complex sustainability challenges. It focuses on developing computational methods and models to understand, manage, and promote sustainable practices in various domains, such as energy, water resources, biodiversity, and urban systems.
Computational social science is an interdisciplinary field that applies computational techniques and models to study social phenomena and human behavior. By leveraging data from various sources—such as social media, surveys, sensor data, and online interactions—researchers can analyze complex social dynamics, patterns, and trends. Key components of computational social science include: 1. **Data Collection**: Utilizing large datasets, often derived from digital interactions and transactions, to gather evidence about social behavior.
Computational journalism is an interdisciplinary field that combines traditional journalism practices with computational methods and tools to enhance reporting, analysis, and storytelling. It leverages data, algorithms, and technologies to gather, process, and analyze information, enabling journalists to uncover insights and present complex stories more effectively. Key aspects of computational journalism include: 1. **Data Journalism**: The use of large datasets to inform reporting. Journalists may analyze public records, social media data, or other datasets to uncover trends and patterns.
Computational geophysics is a branch of geophysics that employs computational methods and numerical simulations to solve complex problems related to the Earth's structure, processes, and characteristics. It combines principles from geophysics, mathematics, and computer science to analyze geophysical data, model subsurface phenomena, and simulate various geophysical processes. Some key aspects of computational geophysics include: 1. **Modeling and Simulation**: It involves creating numerical models of geological and geophysical systems.
Computational epidemiology is an interdisciplinary field that applies computational methods, models, and simulations to study and analyze the spread of infectious diseases and other public health issues. It combines principles from epidemiology, mathematics, computer science, and statistics to understand how diseases propagate through populations, to forecast outbreaks, and to inform public health interventions. Key aspects of computational epidemiology include: 1. **Modeling Disease Spread**: Using mathematical and computational models to simulate how diseases spread in populations over time.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact