Carlos G. Dotti was first author of the 1988 study following axon and dendrite formation in cultured hippocampal neurons. [ref]
The establishment of polarity by hippocampal neurons in culture by Carlos G. Dotti and others. 1988, byline and abstract: establishment of neuronal polarity
The approach made a general cell-biological problem concrete: one cell develops compartments with different structures and functions. Following development in culture allowed temporal evidence to be combined with molecular markers of compartment identity. New to topics? Read the docs here!