 Direct volumetric blood flow measurement in coronary arteries by thermodilution by Wilbert Aarnoudse and others

Wilbert Aarnoudse and colleagues, Journal of the American College of Cardiology 50(24), 2294–2304 (2007), DOI doi.org/10.1016/j.jacc.2007.08.047 . Primary byline and abstract, Methods: continuous saline infusion with an infusion catheter and pressure/temperature-sensing guidewire; validation in five dogs and 35 patients. The method estimates volumetric flow, not blood oxygen content.

Additional precise locators from the primary indexed abstract: Methods specifies a 2.8-F infusion catheter and a 0.014-inch pressure/temperature-sensing guidewire. Results gives the canine comparison regression $Q_{\mathrm{thermo}}=0.73Q+42mL/min$, with $R^2=0.72$.