J. Heinrich Matthaei coauthored experiments with Marshall Warren Nirenberg using cell-free protein synthesis and synthetic polyribonucleotides to investigate the genetic code.
Supplying a simple RNA template and measuring amino-acid incorporation connects nucleotide sequence with protein composition. The experiment separates the informational role of the template from the catalytic machinery already present in the extract.[ref]
The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides by Marshall Warren Nirenberg and J. Heinrich Matthaei. Primary publication: scientific topic and stated experimental result
Portrait of J. Heinrich Matthaei
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