 Mechanism and utility of an RNA-cleaving DNA enzyme by S. W. Santoro and G. F. Joyce

Primary research, Biochemistry 37(38), 13330–13342 (1998), DOI 10.1021/bi9812221. Indexed original byline S. W. Santoro and G. F. Joyce. Abstract reports cleavage kinetics and substrate-binding limitation of catalytic efficiency. This result does not establish universal product-release limitation. The serial-step calculation in the article is an independent model.