 Solution

On the principal open subscheme $D(a)\subseteq \mathrm{Spec}A$, the induced morphism of sheaves is the ring homomorphismIf $\alpha$ is injective, this map is injective by exactness of localization: it is the localization of the injective $A$-module map $A\to B$. Explicitly, if the displayed fraction vanishes, some power of $\alpha (a)$ annihilates $\alpha (b)$; injectivity gives $a^{m}b=0$, so the original fraction also vanishes. The principal opens form an open basis, so the kernel sheaf is zero on a basis and hence zero everywhere. Conversely, an injective morphism of sheaves induces an injection on global sections. On the whole affine scheme these sections are $A\to B$, exactly $\alpha$. Thus