Solution

ID: past-exam-of-the-options-i-course-of-the-university-of-oxford/2008/o/o1/v/solution

The recessive alternative distinguishes CC from the other two types while assigning CT and TT the same disease-risk category. Pooling those two types therefore removes a distinction that this alternative does not use. The resulting counts are for cases and for controls, arranged as CC versus non-CC.
The resulting two-by-two table has reference degree of freedom. Since , reject no association at the five-percent level using the supplied chi-squared test. The observed CC proportion is higher among cases, , than among controls, , so the direction agrees with the proposed increased-risk category.

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