A transformation that makes representations of similar inputs less overlapping, helping reduce interference between stored events. It must retain enough information for useful downstream learning and retrieval. The dentate gyrus is a proposed substrate, with quantitative input–output evidence from spatial cue-conflict experiments.[ref]
CA3 retrieves coherent representations from degraded input: direct evidence for CA3 pattern completion and dentate gyrus pattern separation by Joshua P. Neunuebel and others. Abstract; simultaneous DG/CA3 recordings during local/global cue conflict
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