A propagated outbreak spreads through transmission from infected hosts to further hosts, producing successive infection generations. The transmission route can involve direct contact, a shared vehicle or a vector. Separated peaks in an epidemic curve can be suggestive, but overlapping transmission generations need not give visibly separated waves.[ref]
Principles of Epidemiology in Public Health Practice by the Centers for Disease Control and Prevention. Lesson 1, section 11, Epidemic Patterns: propagated and mixed outbreaks
For an elementary branching approximation, let count infections in generation and suppose each infectious host generates an average new infections while susceptibility remains effectively unchanged. Then and . Starting from one infection with gives expected generation sizes . This is a mean calculation, not a guarantee that every introduction survives: random transmission can produce extinction.
The generation interval controls the timing between infection generations. Depletion of susceptible hosts, changing contacts or interventions can change the effective reproduction number, invalidating the constant- approximation. A common-source outbreak can seed this mechanism, so distinguishing the initial source from later transmission is part of reconstructing the outbreak.
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