A Rab-family regulator associated with early endosomal membrane domains.
Active Rab5 recruits partners that organize early endosomes and membrane fusion. Replacement of Rab5-associated identity by Rab7-associated identity helps connect early uptake with later degradative trafficking, rather than requiring each endosome to retain one permanent molecular label. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapters 3, 6 and 15, protein function, translation and cell signalling
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