A Rab-family regulator associated with late endosomal and degradative trafficking.
Its effectors help connect late endosomes to movement, targeting and fusion with degradative compartments. The transition from Rab5 to Rab7 illustrates maturation of membrane identity; a static marker image captures a state rather than the whole trafficking history. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapters 3, 6 and 15, protein function, translation and cell signalling
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