Robert C. Honey studies associative learning and the contribution of the hippocampus to behavior. His lesion experiment compared responses to audiovisual sequences that preserved familiar components while changing their trained relationship. Such a comparison separates detection of an unfamiliar item from detection of a mismatch between expected associates. [ref]
Hippocampal lesions disrupt an associative mismatch process by Robert C. Honey and others. 1998, rat hippocampal lesions and audiovisual sequence comparisons
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