 Simplifying MS1 and MS2 spectra to achieve lower mass error, more dynamic range, and higher peptide identification confidence on the Bruker timsTOF Pro by Daryl Wilding-McBride and others

PLOS ONE 17, e0271025 (7 July 2022), DOI 10.1371/journal.pone.0271025. Primary byline Daryl Wilding-McBride verified. Isotope-intensity inference section and Figures 7–10: saturated isotopic signals reconstructed from an unsaturated isotope under a peptide-distribution model. The article does not adopt the study’s raw-intensity saturation threshold as a universal detector limit.